UTSA vs. South Florida Prediction, Thursday NCAAF Picks: Target Bryum Brown

UTSA vs. South Florida Prediction: Thursday NCAAF Picks

UTSA (4-4) is set to face South Florida (6-2) on Thursday night in an American Athletic Conference (AAC) showdown at Raymond James Stadium in Tampa. The Bulls, led by quarterback Byrum Brown, have one of the nation’s most dynamic offenses. However, their recent narrow loss to Memphis ended their College Football Playoff hopes.

The Roadrunners and QB Owen McCown look to build on a strong 48-26 victory over Tulane last week as they aim to return to .500 in conference play.

Matchup Breakdown

South Florida plays at a lightning-quick pace, ranking 2nd fastest in seconds per play.
UTSA takes a more methodical and balanced approach to the game.
The Bulls showcase a dual-threat quarterback in Byrum Brown.
The Roadrunners hold a recent series advantage after a 49-21 win over USF in 2023.

Prediction and Key Picks

This primetime AAC matchup kicks off at 7:30 p.m., with both teams fighting to secure bowl eligibility. Our college football pick highlights prime PrizePicks players Byrum Brown and Owen McCown as key targets for bettors.

"Both teams remain in the thick of the AAC bowl picture, but the Roadrunners hold the edge in the series — collecting a 49-21 victory over the Bulls in 2023."

Expect a clash of styles as South Florida's rapid tempo meets UTSA’s steady execution in a key conference battle.

Summary

This AAC game features South Florida’s explosive offense against UTSA’s balanced strategy, with both teams fighting to strengthen their bowl chances after recent big wins and tough losses.

Author’s note: This game highlights a strategic contrast between South Florida’s speed and UTSA’s control, making it a compelling watch for AAC fans.

PrizePicks — 2025-11-06